Marie Claire Marie Claire
  • Celebrity
  • Fashion
  • Beauty
  • Culture
  • Power
  • Nice Talk
  • More
    • Politics
    • Career & Money
    • Health & Fitness
    • Power Play
    • Travel
    • Promo Codes
    • Food & Cocktails
    • About Us
    • Subscribe
    • Sex & Love
  • Newsletter SIGN UP TO OUR NEWSLETTER
  • Marie Claire
    Marie Claire Newsletter

    Celebrity news, beauty, fashion advice, and fascinating features, delivered straight to your inbox!


    By submitting your information you agree to the Terms & Conditions and Privacy Policy and are aged 16 or over.

    You are now subscribed

    Your newsletter sign-up was successful


    Want to add more newsletters?

    Marie Claire Daily

    Delivered daily

    Marie Claire Daily

    Get exclusive access to fashion and beauty trends, hot-off-the-press celebrity news, and more.

    Marie Claire Self Checkout

    Sent weekly on Saturday

    Marie Claire Self Checkout

    Exclusive access to expert shopping and styling advice from Nikki Ogunnaike, Marie Claire's editor-in-chief.

    Maire Claire Face Forward

    Once a week

    Maire Claire Face Forward

    Insider tips and recommendations for skin, hair, makeup, nails and more from Hannah Baxter, Marie Claire's beauty director.

    Livingetc

    Once a week

    Livingetc

    Your shortcut to the now and the next in contemporary home decoration, from designing a fashion-forward kitchen to decoding color schemes, and the latest interiors trends.

    Homes & Gardens

    Delivered Daily

    Homes & Gardens

    The ultimate interior design resource from the world's leading experts - discover inspiring decorating ideas, color scheming know-how, garden inspiration and shopping expertise.


    An account already exists for this email address, please log in.
    Trending
    • Reformation x Alexa Chung
    • 2026 Beauty Awards
    • Fall Movies
    • Being Black at Bravo
    • Slouchy Handbags
    1. Beauty
    2. Skincare

    Retinol vs. Retinoids: A Dermatologist Breaks It Down

    Your best skin awaits.

    By Chelsea Hall
    Published 15 March 2021 In Features

    When you purchase through links on our site, we may earn an affiliate commission. Here’s how it works.

    retinol vs retinoids
    (Image credit: Leandro_Crespi)
    • Facebook
    • X
    • Pinterest
    Share this article
    Join the conversation
    Follow us
    Add us as a preferred source on Google
    Subscribe to our newsletter

    Ask just about any respected skin pro, and they'll tell you that incorporating a retinoid product into your skincare routine is non-negotiable. Retinoids, a family of ingredients derived from vitamin A, are potent ingredients that have been clinically proven to diminish acne, prevent wrinkles, fade dark spots, reverse sun damage, and more. One particularly common form of retinoid is retinol, which is often found in serums and moisturizers, and can be purchased over the counter. A stronger, prescription-only iteration is tretinoin (better known by the brand name Retin-A). Confused? While the terms are often used interchangeably, it's important to understand that there are some distinct differences.

    To help navigate the ins and outs of the retinoid family, I spoke with board certified dermatologist and co-founder of 4.5.6 Melanin Skincare Dr. Carlos A. Charles. Keep reading as he breaks down the key differences, best practices for use, and noteworthy products.

    Retinoids

    What is a retinoid?

    Latest Videos FromMarie Claire
    Watch full video here:

    "Retinoids are the gold standard for treating acne and various skin concerns such as fine lines, improving skin texture, and reversing signs of hyperpigmentation," explains Dr. Charles. "When used topically, retinoids help to increase skin cell turnover and build collagen among other vital functions."

    The powerful ingredient, derived from vitamin A, comes in topical and oral forms, and may require a prescription depending its strength.

    You may like
    • a person with curly hair and perfect skin framed next to three retinol alternative skincare products I Don't Use Retinol—But These Alternatives Still Deliver Impressive Results
    • collage of red blue purple bubbles with girls with good skin and two skincare products that have azelaic acid and retinol Derms Say This Powerful Skincare Duo Is Seriously Underrated for Clear Skin
    • a girl applying serum framed on the back of a serum textured background next to two blue and silver serum bottles If You Don't Have Time for Lasers or a Facial, This Serum Is the Next Best Thing

    How should I use retinoids?

    Dr. Charles recommends incorporating a retinoid product into your nighttime skincare routine. "Ultraviolet light not only heightens your skin's sensitivity but it can also make several retinoids inactive," he explains. "When introducing them into a skincare regimen it should be done gradually. I encourage patients to start by applying a pea size of the product once or twice per week at bedtime for the first three to four weeks before gradually increasing the frequency based on tolerance. Additionally, applying a gentle moisturizer such as Cerave PM or Cetaphil before and after the application of the product can help minimize dryness and irritation."

    Marie Claire Newsletter

    Celebrity news, beauty, fashion advice, and fascinating features, delivered straight to your inbox!

    By submitting your information you agree to the Terms & Conditions and Privacy Policy and are aged 16 or over.

    What are the risks of retinoids?

    Even when used alone, retinoids have the potential to cause irritation when introduced into your regimen. However, mixing them with other active ingredients heightens your skin's sensitivity level and can cause severe dermatitis. "It is best to avoid skincare products containing various acids, benzoyl peroxide, and topical agents used to treat hyperpigmentation," advises Dr. Charles. Ultimately, if you are a beginner or have sensitive skin, make sure to closely review your current skincare routine before adding any retinoid.

    Retinols

    What is retinol?

    What to read next
    • a mature woman framed out next to products to firm loose or sagging skin I Polled Derms to See if This Viral Serum Will Actually Firm Sagging Skin
    • collage of models with clear skin next to skincare products like cleanser, moisturizer and a sunscreen I Watched My Fine Lines Disappear Once I Swapped My Skincare Order
    • a serum texture background with a girl in a black tank top outside next to two peptide serums from Medik8 and Estee Lauder This Derm-Beloved Peptide Serum Is Dubbed “Botox in a Bottle” for a Reason

    "Retinol is an over-the-counter, milder [class] of retinoid," explains Dr. Charles. Retinol is less potent than its prescription counterparts and has fewer side effects, but takes a longer period of time and constant use to show results. It is oftentimes formulated with other hydrating ingredients like hyaluronic acid and antioxidants to make user-friendly serums, moisturizers, and masks.

    "Retinols can be incorporated into the skincare routine at various time periods depending on someone's overall skin goals," says Dr. Charles. "Many of my patients will start using a retinol or even a prescription-strength retinoid in their late twenties and early thirties, along with daily broad spectrum sunscreen to combat sensitivity."

    What are the side effects of retinol?

    The most frequent side effects of retinol occur in the beginning stages of use. "The symptoms commonly experienced include skin peeling, mild sensitivity, and occasional increase in acne activity. These symptoms tend to subside as the skin becomes accustomed to the retinol," says Dr. Charles, citing two to three weeks for skin to adjust. Again, slowly introduce retinol into your routine and listen to your skin to minimize side effects.

    Should I use a retinoid or a retinol?

    Retinoids are an anti-aging gem, a go-to solution for combating breakouts, uneven texture, and pretty much your skin's best friend—when used correctly. If you're looking to take a mild, preventative approach to skin improvement, start with a serum or moisturizer that includes low-dose (0.03 percent) retinol.

    If you're dealing with heavier, chronic acne flareups, speak with your dermatologist to see if you're a candidate for a prescription-strength retinoid. Trust us—blemish-free, glowier skin days are in your future.

    Press Restart Gentle Retinol Serum

    Versed Press Restart Gentle Retinol Serum
    $21.99 AT DERMSTORE.COM

    Retinol Reform®

    Shani Darden Skin Care Retinol Reform®
    $30.00 AT SEPHORA.COM

    Retinol Complex Serum

    Naturium Retinol Complex Serum
    $20.00 AT TARGET.COM

    Neutrogena Ageless Intensives AntiWrinkle Retinol Cream with Hyaluronic Acid Night Moisturizer Cream with Retinol, Vitamin E, Glycerin, Hyaluronic Acid, and Shea Butter, 14 oz

    Neutrogena Anti-Wrinkle Deep Wrinkle Night Moisturizer
    $15.95 AT AMAZON.COM

    Granactive Retinoid 2 Emulsion

    The Ordinary
    $9.80 AT SEPHORA.COM

    A HighDose Retinoid Serum

    Sunday Riley A+ High-Dose Retinoid Serum
    $85.00 AT DERMSTORE.COM

    Adapalene Prescription Strength Retinoid Gel 01 Acne Treatment

    Differin Adapalene Prescription Strength Retinoid Gel 0.1% Acne Treatment
    $12.26 AT AMAZON.COM

    Squalane PhytoRetinol Serum

    Biossance Squalane + Phyto-Retinol Serum
    $72.00 AT SEPHORA.COM

    Explore More
    skincare
    Chelsea Hall
    Social Links Navigation

    Chelsea Hall is the former Assistant Fashion and Beauty Editor at Marie Claire, where she covered celebrity style, fashion trends, skincare, makeup and anything else tied into the world of fashion and beauty

    Read more
    a person with curly hair and perfect skin framed next to three retinol alternative skincare products
    Skincare I Don't Use Retinol—But These Alternatives Still Deliver Impressive Results Pregnant? Sensitive skin? We gotcha.
    By Stephanie (Griffin) Napolitano
    a mature woman framed out next to products to firm loose or sagging skin
    Skincare I Polled Derms to See if This Viral Serum Will Actually Firm Sagging Skin When I turned 35, naturally, I got curious.
    By Olivia Truffaut-Wong
     
     
    a young woman with dark curly hair and glowing skin next to two bottles of copper peptide skincare
    Skincare Here's Why Your Dermatologist Is Obsessed with Copper Peptides Wrinkles and fine lines? Never met them.
    By Allison Lax
    Shiseido Vital Perfection SculptDefine Serum on a womens face next to the bottle and ingredients
    Skincare Shiseido Says This $155 Serum Will Lift My Skin in a Week—But Does It Work? I put the new formula to the test.
    By Siena Gagliano
     
     
    Latest in Skincare
    Rodan + Fields
    Skincare We're Convinced This Vitamin C Serum Will Dethrone the Most Effective One in Your Routine
    Rodan + Fields
    Skincare Let's Get Real About Perimenopausal Skin, Okay?
     
     
    a woman using a gua sha next to the barbara sturm super antiaging face mask rich
    Skincare This 20-Minute Treatment Is My Secret to Erase Morning Puffiness
    versed products on a purple backgorund next to models
    Makeup I Don’t Know How This 10/10 Drugstore Brand Is Still Flying Under the Radar
     
     
    Latest in Features
    dyson camerajet
    Beauty Was the $500 Plaque-Fighting Dyson Toothbrush Too Good to Be True?
    side by side images of a party with marie claire branded glass trophies and paper bags, with lots of flowers
    Beauty We Celebrated Our 2026 Beauty Awards In Style—Here's a Peek Inside the Party
     
     
    Black-and-white photo of a person walking past a Cornell University stone sign, with their face obscured by a teal scribble.
    Politics What the Morning After a Sexual Assault On Campus Really Looks Like
    Rare Beauty & BÉIS collaboration of hot pink luggage and makeup in a collage featuring shay and selena
    Beauty BÉIS x Rare Beauty Collab Is Back With a Color You’ll Never Lose at Baggage Claim
     
     
     
     
     
     
     
     
    Marie Claire
    RSS
    • About us
    • Contact Future's experts
    • Contact us
    • Advertise Online
    • Newsletter
    • Terms and conditions
    • Privacy policy
    • Cookies policy
    • Careers
    Add as a preferred source on Google Add as a preferred source on Google

    Marie Claire is part of Future US Inc, an international media group and leading digital publisher. Visit our corporate site.

    © Future US, Inc. Full 7th Floor, 130 West 42nd Street, New York, NY 10036.