The Best Skincare Routine for Acne, According to Dermatologists

Every product to include in your morning and nighttime regimen.

model with bright eye makeup and acne
(Image credit: Dominik Bindl/Getty )

So, you have acne. It’s something 90 percent of people (not just teens) deal with—and getting it under control can be a freakin’ challenge. The thing is: There's not one magic pill, spot treatment, or hard and fast skincare routine for acne that’s going to make blackheads, whiteheads, or nasty cysts poof and disappear. Figuring out the right cocktail of over-the-counter products, active ingredients, and prescription medications that will move you towards a clearer, less angry complexion can be a journey. While there’s no exact recipe for blemish-free skin (le sigh), there are a few do’s, some don'ts, and a handful of ingredients to seek out. 

“The best skincare routine is simple and easy to follow,” explains Dr. Joshua Zeichner, a board-certified dermatologist. “If you are acne-prone, the acne treatment is usually top priority.” And while spot treatments and over-the-counter products can be game-changing (we’re breaking down our favorites ahead), working with a dermatologist is hands-down the most important factor in the equation. “We are limited in what’s available over-the-counter, so that’s best suited for mild acne. If you are getting cystic breakouts, darkening of the skin, hyperpigmentation, scarring, or dealing with anything more moderate or severe, you must see a dermatologist,” adds Dr. Shari Marchbein, board-certified dermatologist and founder of Niche Dermatology NYC. 

With that in mind, we’ve streamlined your skincare shopping list and created a guideline for the best skincare routine for acne. We’re breaking down the steps that belong in your morning and nighttime routines, explaining how to incorporate active ingredients or acne treatments, and rounding up the best, pimple-fighting and non-irritating products out there. 

How Do You Know If You Have Acne-Prone Skin?

Determining your skin type isn’t cut and dry. You can be oily and acne-prone, dry and acne-prone, sensitive and acne-prone—the list goes on. You can also have oily skin and rarely, if ever, develop a pimple. It all boils down to how your skin’s sebum (the technical term for oil), dead skin cells, and debris interact with your pores. “Someone with acne-prone skin is more than just being oily. If you are acne-prone, it means that not only do you produce high levels of oil, but also that oil becomes trapped within the pores,” explains Dr. Zeichner. 

There’s also different types of severity to consider when talking about acne. Those with mild acne might have a cluster breakout here or there. Some people might flare with their menstrual cycle, and others might find that the prevalence of their pimples are connected to their food intake. More moderate or severe acne can consist of painful cysts, chronic breakouts, or lead to acne scars.

Yes, You Can Develop Acne-Prone Skin as an Adult

There’s a big misconception that acne is reserved exclusively for the teenage years. That couldn’t be farther from the truth. In fact, 12 to 22 percent of adults deal with regular breakouts. You could live your entire adolescence without ever putting a spot treatment on a blemish, only to develop severe acne in your 20s, 30s, or 40s. Dr. Marchbein explains that this “adult female acne” is typically hormonal in nature. “The main treatment is going to be controlling the hormones,” she explains. 

The two most common treatments to regulate hormones, and in turn oil production, is via birth control pills and a drug called Spironolactone. While the latter is not technically designed to treat acne, it’s widely accepted as a “very, very safe” treatment and has hundreds of studies to back up its efficacy as an acne treatment. 

The Best Skincare Routine for Acne

Morning and nighttime skincare routines are always going to differ slightly (SPF in the a.m., acids in the p.m.), but broadly speaking the best skincare routine for acne is going to cleanse, treat, and hydrate. And while it can be tempting to throw every product with the phrase “acne fighting” at your skin, that’s not the best course of action. 

“More is not necessarily better,” says Dr. Zeichner. “Over washing or over scrubbing the skin can disrupt the skin barrier, leading to irritation and inflammation, which makes it more difficult to treat acne.” 

Instead, look for products that are gentle, oil-free, and non-comedogenic, which is a fancy way of saying the ingredients won’t clog your pores or cause pimples. “Make sure you are using serums and masks that are appropriate for people with acne prone skin,” adds Dr. Zeichner.  “Avoid heavy oils like avocado, olive oil or squalene which may lead to breakouts.” 

The Best Morning Skincare Routine for Acne


When you wake up in the morning, reach for either a gentle foaming cleanser that’ll remove excess oil from your skin, or a face wash with a built-in salicylic acid or benzoyl peroxide treatment. “Studies have shown that anywhere between four to 10 percent of benzoyl peroxide are equally as effective—and 10 percent can be a little irritating,” explains Dr. Marchbein. She recommends looking for a product that’s balanced out with hydrating ingredients. “CeraVe for example makes a nice four percent cream wash that has ceramides and glycerin [to soothe the skin.]” 


Daytime acne treatments can be broken up into two categories. If you have mild acne and aren’t seeing a dermatologist, seek out over-the-counter products that target acne. If you have more mild, severe, or chronic acne and are working with a dermatologist, a topical cream is likely going to be in your regimen. 


If you’re planning to create an acne-fighting routine with over-the-counter products, Dr. Zeichner recommends diversifying your acne treatment. So, if you used a benzoyl peroxide face wash for instance, try a salicylic acid treatment—and vice versa. “Sticking to all the same ingredients is not as effective as combining different active ingredients that complement each other and their mechanisms of action,” he explains. 

It’s also worth noting that acne products are considered drugs, are regulated by the FDA, and are safe and effective. Instructions should be carefully followed on any treatment product containing benzoyl peroxide, sulfur, or salicylic acid. 

Prescription Creams

If in-store products simply aren’t cutting it or you just want to take your multitude of skin problems straight to a pro, visiting a dermatologist brings about a whole new world of acne treatments. While we’ll dig into oral medications later, we also want to dive into topical creams and gels that can work wonders. 

“Our topical acne medicines treat about 30 percent of acne lesions, so it’s really about the way we combine things together. That’s where a dermatologist comes in to combine different topicals in a way that’s effective,” says Dr. Marchbein. “You might just have plain acne, you might have acne and rosacea and sensitive skin, you might have acne, rosacea, and periorificial dermatitis. There’s so many different options for the type of breakouts that you have.” 

Your dermatologist will be able to create a routine and mash up of ingredients that work for you, targeting inflammation, hormones, or bacteria. Dr. Marchbein “loves topical Dapsone” for her adult acne patients, but other topical prescriptions include Clindamycin and Winlevi. 


Oily skin and acne? Don’t get it twisted: you still need to moisturize acne-prone skin. Maintaining a hydrated and healthy skin barrier is *extremely* important—especially if you’re using treatment products. “Damaging the skin barrier can cause a worsening of acne. That’s why over scrubbing or overdoing it with harsh products can make acne worse,” says Dr. Marchbein. “[You need] products to prepare and soothe the skin barrier, because the medications are often drying and irritating.” 

Just make sure to look for non-comedogenic, lightweight, and oil-free formulas that are packed with hydrating ingredients like ceramides and hyaluronic acids.