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    1. Beauty
    2. Skincare

    I Tried the Biossance Squalane + Growth Factor Firming Moisturizer and My Ultra-Sensitive Skin Is So Grateful

    The latest addition to the brand is well-worth the hype.

    Christina DAmbrosio's avatar
    By Christina DAmbrosio
    Published 29 December 2025 In Buying Guides

    When you purchase through links on our site, we may earn an affiliate commission. Here’s how it works.

    Biossance Squalane + Growth Factor Firming Moisturizer
    (Image credit: Biossance)
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    As a founding member of the sensitive skin club, I have tried what feels like every product under the sun in search of formulas that won’t send my eczema-prone skin into a spiral. Keeping my epidermis healthy is challenging enough, but when you add sub-freezing temperatures into the mix, the quest for hydrated skin feels never-ending. Lucky for me, I think my endless trial and error have come to an end, and I’ve (nearly) perfected my winter skincare routine. Enter: Biossance's Squalane + Growth Factor Firming Moisturizer.

    If you don’t already know, Biossance is a vegan skincare brand that uses plant-based squalane as a hero ingredient in many of its products. While squalane was historically sourced from shark livers, the brand’s version is derived from sugarcane—which results in a “purer, vegan, more ethical, and more effective” ingredient. The compound occurs naturally in our skin, but when used in skincare it promotes hydration and can help boost absorption of other active ingredients.

    Naturally, when I heard Biossance had a new moisturizer hitting shelves, I jumped at the chance to give it a try. Turns out, the just-launched Squalane + Growth Factor Firming Moisturizer is just what my skin’s been craving.

    Biossance Squalane + Growth Factor Firming Moisturizer

    Biossance
    Squalane + Growth Factor Firming Moisturizer
    $64
    SHOP NOW

    The Ingredients and Formula

    The Squalane + Growth Factor Firming Moisturizer aims to support the skin barrier and promote elasticity through the use of four main ingredients. First up is the brand’s biomimetic Growth Factor—a vegan protein identical to those naturally occurring in the skin—which encourages cells to “act and appear younger.” Then, a powerhouse combination of cyclic peptides, vegan collagen, and sugarcane squalane comes together to plump, firm, and hydrate the skin.

    According to the brand, the formula delivers both immediate and long-term benefits by helping restore the look of collagen-rich skin while visibly improving laxity, firmness, and reducing the appearance of fine lines.

    Christina DAmbrosio using Biossance Squalane + Growth Factor Firming Moisturizer with and without makeup.

    Christina DAmbrosio using Biossance Squalane + Growth Factor Firming Moisturizer with and without makeup.

    (Image credit: Christina DAmbrosio)

    The Application

    As a longtime Biossance fan, this product is a welcome addition to their existing lineup. My current everyday moisturizer is the Squalane + Omega Repair Cream, which has a rich, whipped formula. The Squalane + Growth Factor, however, is cushiony, with a gel-like consistency. Like the other products in their line, this moisturizer has a bit of a sweet scent, thanks to the sugarcane-based squalane. This can be jarring at first, but you get used to it.

    I applied the moisturizer as directed—on cleansed skin, following my eye cream and serum routine. It feels cool on application, soothing my easily-aggravated skin. Since I’m already familiar with the Squalane + Omega cream, I was a little surprised by how light this product is in comparison. However, its hydrating benefits are noticeable upon application, drying down to a lightweight, silky finish.

    I definitely think going in with a copper peptide serum first helped secure a bit more moisture on my ultra-dry patches, ultimately resulting in a nice, glowy complexion. It layered nicely under makeup, but I likely need to wait a bit longer between steps due to the tackiness of the moisturizer.

    Christina DAmbrosio holding the new Biossance Squalane + Growth Factor Firming Moisturizer.

    Christina DAmbrosio holding the new Biossance Squalane + Growth Factor Firming Moisturizer.

    (Image credit: Christina DAmbrosio)

    The Takeaway

    The ingredients in this product really put it in a class of its own within my skincare stash. I appreciate that it feels totally different from other products that I already use, and that it actually works in tandem to boost their effectiveness. I was especially impressed with how well it locked in hydration during a sub-freezing week in New York City, preventing my skin from turning into a flaky mess. I don’t see it outright replacing my tried-and-true, but it’s definitely a nice option to have as a complement to my existing routine.

    Other Biossance Favorites

    Squalane + Omega Repair Cream

    Biossance
    Squalane + Omega Repair Cream
    $60
    SHOP NOW

    Squalane + Copper Peptide Rapid Plumping Serum

    Biossance
    Squalane + Copper Peptide Rapid Plumping Serum
    $88
    SHOP NOW

    Firm and Lift Hydrating Dual Serum With Hyaluronic Acid + Squalane

    Biossance
    Firm and Lift Hydrating Dual Serum With Hyaluronic Acid + Squalane
    $68
    SHOP NOW

    Why Trust Marie Claire

    For more than 30 years, Marie Claire has been an internationally recognized destination for news, fashion, and beauty trends, investigative packages, and more. When it comes to the products Marie Claire recommends, we take your faith in us seriously. Every product that we feature comes personally recommended by a Marie Claire writer or editor, or by an expert we’ve spoken to firsthand.

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    Marie Claire Newsletter

    Celebrity news, beauty, fashion advice, and fascinating features, delivered straight to your inbox!

    By submitting your information you agree to the Terms & Conditions and Privacy Policy and are aged 16 or over.
    Christina DAmbrosio
    Christina DAmbrosio
    Deputy Director of Social Media

    Christina DAmbrosio is the Deputy Director of Social Media at Marie Claire. She is an Emmy-nominated producer with prior experience at Paramount, where she led the social media strategy for major franchises including RuPaul’s Drag Race and Yellowjackets. Christina also has experience at Elite Daily, Business Insider, and The Knot. Originally from Boston, she graduated from Fordham University and has been based in New York City ever since. In her free time, she enjoys going to concerts, seeing Broadway shows, and watching reality TV. Find her on social at @christinadambro.

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