Look, good things rarely happen in Game of Thrones. Typically, the worst scenario you can think of is often exactly what will take place. And at the end of Sunday night's episode, two concerning things happened: 1) Bronn used the Qyburn Industries™-developed anti-dragon missile to shoot down Daenerys and her dragon, Drogon. 2) Jaime, about to get his dumb ass torched, was shoved into a curiously deep lake by Bronn and started sinking to his watery grave. Both are bad things! But, as great as Jaime's character is, it would be totally devastating if Drogon died. The dragons can't die, right? Well, that's what we thought about Ned Stark, and that didn't go so well.
Some fans have noticed some disturbing parallels between Drogon and his namesake, Khal Drogo:
I loved how poetic it was that Drogon, the dragon named after Khal Drogo, was the one leading the Dothraki attack on the Lannisters. It just seems to [sic] perfect that not only was Drogon leading the attack, but he also suffered the same injury as Drogo, an attack to the shoulder (albeit, opposite shoulder).
As we know, Drogo eventually succumbed to his wounds (in a sense) back in Season 1—a season that's been referred to quite a bit during these last few episodes. And hopefully the parallel doesn't extend to the severity of Drogon's wound. What's also concerning is who built the anti-dragon missile.
Fans have also pointed out that Qyburn has a mastery of f*cked-up, mysterious technologies—including poison. It's very possible that when creating this grand Dragon killing device for Cersei, he knew one missile wouldn't do it. He'd need something a little more sinister—something like a poison that could kill dragons. Now, it's unlikely Qyburn knows much about dragons, but, as book readers know, there's quite a bit of information in history books about the Targaryens' ancient wars and their dragons to maybe pull a recipe together. This show certainly does have an affinity for queens sacrificing their children for power, and Daenerys is the Mother of Dragons.