I Have the Pickiest Nose I Know—These 5 Fragrance Layering Combos Are Elite
They’re perfect for fall, too.


I genuinely don’t remember the last time I sprayed just one fragrance and walked out the door. My perfume collection is 300+ bottles large, and I personally think it would be a disservice not to spread the love. So, I layer. My scented body washes and lotions play a key role, as do fragrance oils, body mists, and hair perfumes. Every day is a different concoction—and through trial and error, I’ve been able to figure out which duos are a recipe for compliments.
That all being said, my combos change with the seasons. And now that we’re firmly in the grips of fall, I’m leaning into all things warm and delicious. Vanilla scents are my personal favorite (I’m a gourmand girl, what can I say), but I try to spread the love across most of the fragrance families. To find out my fave fall fragrance layering combinations, keep reading.
Double Down on Vanilla Perfume
I am a vanilla girl through and through. I’ve embraced the Vanilla Renaissance with wide open arms and easily added dozens of sophisticated (but still yummy) grown-up gourmands to my collection. To avoid smelling like a sweet treat, I look for rich and deep vanillas that are oftentimes balanced with woody notes. Nine times out of 10, this my go-to fall combo.
If you want a rich scent that smells like the sexiest, most expensive vanilla extract on planet Earth, this is your girl. It’s an extrait, so a little goes a long way and expect it to last forever. That being said, it’s pretty straightforward on the vanilla front, so I like to add dimension with my second fragrance.
This perfume really does smell different on everyone—but my skin picks up more of the woody notes than the vanilla ones. But! That makes it the perfect companion to Deep Dark Vanilla. It’s truly the ideal ratio of woody to vanilla. Think: mature but still sweet.
My Go-To Boozy Blend
Alcohol-inspired fragrances are having a mega-moment. Don’t get it twisted though—I’m not out here trying to smell like I had one too many. Boozy perfumes often smell sexy and moody, evoking feelings of a late night at a cocktail bar. I gravitate toward this combo for a date night. Trust me: it’ll get noticed.
A Marie Claire 2025 Fragrance Award winner, this perfume is genuinely one of my favorite discoveries. It’s creamy and addictive—like a really seductive scene of bourbon next to a decadent French vanilla sundae.
A Little Leather Fragrance
I’m all for a manly, unisex fragrance layering combo. It’s mature and sophisticated and makes me smell more mysterious than I’ll ever be. To me, this combo smells safe and warm, which is ideal for chilly days when I’m breaking out gloves and cashmere.
My dad actually bought this for himself—and I swiftly swiped it off his counter. The juxtaposition of violet and jasmine alongside rich black leather results in a scent that feels truly unexpected and unique. It’s on the heavier side though, so one spray is truly all you need.
Easily one of my favorite new favorite brands to hit the scene, Cyklar has launched some truly iconic perfume oils. They stay close to the skin and don’t compete with your main fragrance. Still, this one offers a musky compliment to the leather—if your close enough to get a whiff.
For a Fresh Scent
This is my Sunday scent. It’s the perfect, light and airy mix for a mental reset day when my activities include doing laundry, grocery shopping, and cleaning my apartment. It’s soft and soothing, calming my mind and giving me a clean-as-can-be feel.
Yes, Zara has perfumes—and they’re honestly really, really good. While I’ll sometimes where Blanche solo, adding a little of this light citrus to the mix gives it a tangy edge. Think: club soda with a hint of lemon or lime.
Spritz a Fruity Mist
While most fruity fragrances can lean summer, I do my very best to make ‘em work for fall. The key: mix a deeper, richer fruit-forward scent with a summer staple to offer a bit of levity. I’ve been wearing this mix on repeat, and it’s a quick fan favorite. I almost never leave the house without getting stopped.
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The cherry perfume trend has been kicking for a hot minute—but this latest launch offers a spin we have yet to see. Instead of harnessing the bursting tartness of a ripe cherry, this eau de parfum uses the cherry stem. It’s simultaneously a bit greener and deeper than the typical cherry scents.
This is my go-to summer fragrance, so I’ve done everything in my power to figure out how to make it fall-friendly. Blending it with Dark Cherry is the key. The fig note in Dioriviera has no problem breaking through, but the richness of Dark Cherry serves as the perfect balance to Dioriviera’s solar fizziness.
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Samantha Holender is the Senior Beauty Editor at Marie Claire, where she reports on the best new launches, dives into the science behind skincare, and shares the breakdown on the latest and greatest trends in the beauty space. She's studied up on every ingredient you'll find on INCI list and is constantly in search of the world's glowiest makeup products. She's constantly tracking the biggest nail and hair trends to pop up in the beauty space, going backstage during fashion weeks, tracking celebrity looks, and constantly talking to celebrity hair stylists, nail artists, and makeup artists. Prior to joining the team, she worked as Us Weekly’s Beauty and Style Editor, where she stayed on the pulse of pop culture and broke down celebrity beauty routines, hair transformations, and red carpet looks. Her words have also appeared on Popsugar, Makeup.com, Skincare.com, Delish.com, and Philadelphia Wedding. Samantha also serves as a board member for the American Society of Magazine Editors (ASME). She first joined the organization in 2018, when she worked as an editorial intern at Food Network Magazine and Pioneer Woman Magazine. Samantha has a degree in Journalism and Mass Communications from The George Washington University’s School of Media and Public Affairs. While at GWU, she was a founding member of the school’s HerCampus chapter and served as its President for four years. When she’s not deep in the beauty closet or swatching eyeshadows, you can find her obsessing over Real Housewives and all things Bravo. Keep up with her on Instagram @samholender.