The 21 Most Iconic Photos of Joan Rivers

Rivers has hosted Fashion Police since September 2010, reaching more than 10 million viewers worldwide, according to her website.

Rivers had considered Prince Charles a friend. He sent her a Christmas present every year and reportedly looked forward to receiving her thank-you notes.

Rivers was president of her condo board.

Rivers won the second season (2009) of The Celebrity Apprentice.

Although Rivers lived on New York City's Upper East Side, she considered her 84-acre Colorado estate home.

Rivers once worked as a publicist for Lord & Taylor.

Mother and daughter starred in four seasons of the reality show Joan and Melissa: Joan Knows Best?

Melissa Rivers on her mother: "She’s ... completely supportive of gay rights and everyone should be able to do whatever they want, live and let live, and whatever makes you happy. She has no problem with, like a rhino and a ferret living together, and yet she can’t believe that I don’t want to get married again!"

On interviewing celebrities: "You feel like a member of the press corps—you share, and it also gets very competitive. It's like being a fighter and going into the ring. All that energy!"

Dinner-party tips Rivers once gave to The New York Times: Make your guests name something they're grateful for, and put facts about other guests under person's each plate.

When asked if she'd ever regretted anything she'd said, Rivers replied: "Remember all the Elizabeth Taylor jokes, which I did when she was fat? ... I regretted those. So I had a mutual friend call her up, to see if it was hurting her, to say that I was starting to regret this and that I'd stop. And she sent back a message saying, 'It doesn't get me where I live.' From then on, I was crazy about her."

Carson famously refused to speak with Rivers again upon learning Fox had offered her her own show. She finally returned to The Tonight Show in March 2014 with Jimmy Fallon as host.

Rivers conducted her 1,000th interview in 2006.

Her irreverent attitude extended to aging, as illustrated by this tweet:"I must admit I am nervous about getting Alzheimer's. Once it hits, I might tell my best joke and never know it."