$6,500 Bottega Veneta; (877) 362-1715.
The South African ostrich skin is vegetable-dyed, and the trim is hand-painted Bolivian crocodile skin. No two bags are alike.
$3,500 Bally; (310) 271-3310.
They made only 100 of these bags, as it takes three months to treat and lacquer the skin and stitch by hand. Designed by Brian Atwood.
$420 Michael Kors; (212) 965-0401 for other colors.
Or you can cheat a little: Leather from Argentina is tanned for four weeks in Italy, then stamped to look like ostrich.