I Refuse to Spend Hundreds on Skincare—Which Is Why I Love an Affordable Drugstore Serum
Beauty on a budget.
For most of my life, I equated a "good serum" with an "expensive serum." I bought into the idea that if a bottle didn't come in luxe packaging with a three-digit price tag, it couldn't possibly deliver real results. Then I became a beauty editor and began testing everything—with the background knowledge of what skincare ingredients do and how they work—and that belief unraveled quickly. What I've discovered? Some of the most effective face serums live at the drugstore.
Drugstore serums have always been good, but they've leveled up even more over the past decade. You can now find formulas with vitamin C, hyaluronic acid, niacinamide, retinol, peptides, and barrier-repair ingredients for a fraction of what prestige brands charge. And they're not watered-down versions, either. Many are developed in the same labs (yes, really!), by the same chemists, and designed to solve the same skin concerns: dehydration, fine lines, discoloration, breakouts.
What I love about this category is how accessible it makes skincare. For results, you need consistency. (Did you know a vitamin C serum should be used completely within two months?!) When you can afford to actually finish a bottle and repurchase it, that's when you can visibly see the benefits in your skin. Below are the drugstore serums I genuinely use and recommend to everyone in my life.
Siena Gagliano after using a drugstore serum.
Brightening Drugstore Serums
Vitamin C is the ingredient to reach for when your skin needs a pick-me-up. It's one of the most-researched antioxidants with powerful protection against environmental aggressors (hi, UV, pollution and whacky temperatures). It also brightens uneven tone, softens the look of dark spots, and even boosts collagen production. At the drugstore, look for "stabilized" labeling, as those will be less likely to oxidize and become ineffective.
I absolutely love this vitamin C. It has 10 percent L-ascorbic acid, so it's on the gentler side, but it comes in a super-easy gel texture that makes application less messy, and the packaging helps prevent oxidation. It also has no fragrance and contains ceramides to help prevent irritation. It's great for someone with sensitive skin or someone just beginning to use the ingredient.
This K-beauty brand may not be in traditional drugstores just yet, but it is available on Amazon Prime at a drugstore price. It's a more potent vitamin C with 23 percent L-ascorbic acid, so it's strong, and you'll definitely see results. It also contains other MVP ingredients, like niacinamide and licorice root, for a powerful brightening concoction.
Hydrating Drugstore Serums
Everyone needs a hyaluronic acid serum in their skincare arsenal at all times. There are literally no drawbacks to using it, and it's a very gentle, skin-friendly ingredient. It works by pulling water into the skin, which is why my complexion looks smoother and plumper after using it. My tip? Apply a moisturizer rich in occlusives (think: squalane, butters, and petrolatum) to trap the moisture in for extra softness.
I love a French pharmacy skincare pick because those girls are known for their enviably smooth skin. Formulated with mineral-rich water and hyaluronic acid, this Vichy staple has the loveliest gel-serum texture and feels super elegant on skin.
Anti-Aging Drugstore Serums
The term "anti-aging" is definitely an outdated term. We're not trying to stop time; we're just trying to keep skin healthy and resilient as it changes. This category is really about texture and long-term support. Ingredients like retinol help smooth fine lines and encourage cell turnover, peptides support firmness, and sunscreen prevents damage in the first place. While looking for this category at the drugstore, I always recommend a retinol.
This serum offers a high-strength retinol for an over-the-counter product, but requires consistent, long-term use over a few months for results. I particularly love this formula because it also contains antioxidant-protecting vitamin E and soothing chamomile to help mitigate dryness.
Acne-Fighting Drugstore Serums
Acne serums today don't just dry out your skin. Instead, they combine chemical exfoliators and niacinamide with other acne-friendly ingredients to avoid that stripped, irritated feeling. The goal is calmer skin and fewer breakouts without the old-school effects.
The price is so good on this one that it's understandable you might raise your eyebrows and doubt its efficacy. That said, the formula calls on niacinamide—a highly researched and proven acne-fighter—to combat breakouts, dark spots, and uneven texture. It's also fragrance-free and suitable for daily use.
Mandelic acid is having a moment. It's an AHA that's gentle enough for regular use and effective enough to visibly smooth texture and fade dark spots. This formula pairs 12 percent with niacinamide to further enhance smoothness and glow. Naturium's serum resurfaces skin without the sting of stronger acids, all for a wallet-friendly price.
Soothing Drugstore Serums
These serums are ideal for pretty much everything else. Centella asiatica, oat, ceramides, and allantoin help repair the skin barrier and calm inflammation, which makes every active in your routine work and feel better. I always keep these on hand after trying something new, overdoing exfoliation, or just when I want something gentle and calming.
My skin reacts to anything new I've incorporated into my routine. I love Aveeno for its gentle skincare products like this Oat Serum. It uses oat, of course, but it also contains feverfew, an extract known to help soothe irritation and redness, including rosacea.
Cetaphil is as sensitive skin-friendly as skincare can get. Any dermatologist I ask more often than not recommends the brand across all ingredient categories. I adore this serum for its blend of three powerful soothers—ceramides, centella, allantoin—that instantly calms skin upon contact.
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Siena Gagliano is the Beauty Editor at Marie Claire, where she writes and edits reported features, trend stories, and expert-backed shopping roundups. Before joining the team full-time, she was an editor at Cosmopolitan, where she specialized in SEO-first beauty content and commerce strategy. Her bylines have also appeared in Allure, ELLE, Bustle, Well+Good, Popsugar, and Women's Health, covering everything from the best products for brighter, glowier skin to the science behind face mapping. Curious about the behind-the-scenes magazine life and her go-to beauty picks? Follow her on Instagram at @sienagagliano.